St. Innocent Winery was founded in 1988 by owner and winemaker Mark Vlossak. Mark's interest and education in wine began early – his father was a wine importer and Mark produced sparkling wine in 1985-87. He then apprenticed with Fred Arterberry, Jr. at Arterberry, Ltd from 1987-1988. In 1994, he was appointed winemaker at Panther Creek Cellars where he worked for five years before founding St. Innocent.

St. Innocent produces small-lot, handmade wines in the Old World tradition – in other words, wines intended to go with food. The estate vineyard in the Eola-Amity Hills is planted to 16 acres planted to Pinot Nor. The winery also works closely with eight different growers, leasing specific blocks of vineyards to produce terroir-specific wines. A new winery at the Zenith Vineyard was completed in time for the 2007 harvest. This 17,500 sq. ft., four story, gravity facility features underground barrel rooms, a temperature controlled crush floor and a 900 sq. ft. tasting room.